Medicinal chemistry services
Mercachem can work on the following type of projects:
• Design and synthesis of druglike compounds
• Hit optimization
• Lead optimization
• Experimental measurement of physical and chemical properties
The basis of this service from Mercachem is two-fold: the vast experience in pre-clinical research in pharmaceutical industry of our staff, and the broad knowledge in synthetic organic chemistry.
Using a wide variety of optimization tools we can help you to select your candidate compounds. Many tools are available in-house. For more specialized tools we cooperate with established independent CRO's.
Optimization tools available in-house:
• A thorough knowledge of preparative organic chemistry
• Design and synthesis of focused libraries
• SAR studies
• Physico-chemical properties: solubility, stability, LogD, logP.
• Analysis of metabolites
With these tools, projects can be tailored to the needs of the client.
Mercachem is not pursuing a MedChem IP portfolio; intellectual property of the Medicinal Organic Chemistry Projects remains with our client.
We would be pleased to provide you with a more detailed presentation. If you have any questions or remarks, please do not hesitate to contact us. (fact sheet)