Our services

Mercachem offers the following services (fact sheet):

Discovery chemistry

• Synthesis of building blocks and scaffolds
• Synthesis of reference standards and impurities
• Synthesis of metabolites (oxidation and conjugation)
• Synthesis of new chemical entities or analogs for hit-to-lead development
• Feasibility and validation studies towards parallel synthesis of libraries
• Parallel synthesis of focused libraries (10-1000 members) (fact sheet)

Projects are carried out by employing the latest synthetic methodologies and equipment such as heterogeneous and homogeneous catalysis, biocatalysis and microwave chemistry, etc. (fact sheet)

Medicinal chemistry

• Design and synthesis of druglike compounts
• Hit optimization
• Hit-to-Lead
• Lead optimization
• Experimental measurement of physical and chemical properties

Using a variety of optimization tools we can help you to select your candidate compounds. (fact sheet)

Process research

• Route scouting
• Reaction and process optimization
• Catalyst screening
• Material supply (~1 kg, non-GMP)

Design of experiments, multivariate data analysis and parallel experimentation
are used as a tool to rapidly achieve reliable results. (fact sheet)